p5.4xlargeAWS Pricing, Specs & Benchmarks

The p5 family is a generation-5 GPU-accelerated (NVIDIA) line running on Intel Xeon (x86_64). p5.4xlarge provides 16 vCPUs and 256GB of RAM (a 1:16 vCPU-to-memory ratio), priced at $6.8800/hr On-Demand — about $4953.60 per month at 24×7 utilization.

GPU-accelerated (NVIDIA) instances are sized for deep-learning training, large-scale inference, HPC simulation, and any workload that scales with CUDA-enabled GPU compute. If your workload doesn't match that profile — for example, if you're running a memory-bound app on a compute-optimized instance, or a CPU-pegged batch job on a burstable t-series — you'll likely pay for capacity you can't use or run into bottlenecks you didn't anticipate. The pages for sibling families (linked further down) cover those alternatives in detail.

In the AWS instance-naming convention, the digit after the series letter is the generation — higher is newer. This appears to be one of AWS's newer generations in the series, so for most fresh workloads it's a reasonable default within its category.

Pricing varies by region (sometimes meaningfully — the gap between the cheapest and most expensive AWS region for the same SKU is often 15–30%). The regional pricing table further down shows where p5.4xlarge is cheapest today, both On-Demand and Spot. Spot pricing for p5.4xlarge is currently $2.2392/hr — roughly 67% off On-Demand — which makes the instance viable for fault-tolerant batch jobs, CI fleets, and any workload that can tolerate interruption with short notice.